Table 3. . Intra- and inter-day precision and accuracy data for enalapril and enalaprilat in human plasma (n = 6).
| |
Intraday (within run) |
Interday (between run) |
||||||
|---|---|---|---|---|---|---|---|---|
| Mean concentration (ng/ml) | SD | CV (%) | Accuracy (%) | Mean concentration (ng/ml) | SD | CV (%) | Accuracy (%) | |
|
Enalapril | ||||||||
| LQC (3 ng/ml) |
3.0933 |
0.1075 |
3.4738 |
103.1111 |
3.0113 |
0.3226 |
10.7128 |
100.3750 |
| MQC (200 ng/ml) |
223.9300 |
26.4513 |
11.8123 |
111.9650 |
207.6733 |
22.7122 |
10.9365 |
103.8367 |
| HQC (400 ng/ml) |
453.7200 |
35.9618 |
7.9260 |
113.4300 |
425.1263 |
32.8410 |
7.7250 |
106.2816 |
|
Enalaprilat | ||||||||
| LQC (3 ng/ml) |
3.1150 |
0.3038 |
9.7515 |
103.8333 |
2.8988 |
0.3990 |
13.7661 |
96.6250 |
| MQC (200 ng/ml) |
187.9250 |
19.3644 |
10.3043 |
93.9625 |
199.1229 |
23.3814 |
11.7422 |
99.5615 |
| HQC (400 ng/ml) | 393.6150 | 12.2396 | 3.1095 | 98.4038 | 399.9475 | 27.1177 | 6.7803 | 99.9869 |
HQC: High quality control; LQC: Low quality control; MQC: Medium quality control.