Figure 3.

Motif diagram of selected members of the UPF0016 family, including all members of Arabidopsis, yeast and human. Transmembrane helix predictions were performed with TmHMM2.0²⁸ and adjusted manually afterwards. The subcellular localization based on the N-terminal amino acid sequence and the prediction of the respective cleavage site was performed with TargetP1.1.²⁹ Signal peptides were discriminated from transmembrane regions using SignalP4.0.³⁰ The scale bar represents 20 amino acids.