. Author manuscript; available in PMC: 2018 Apr 1.

Published in final edited form as: Crit Care Clin. 2017 Apr;33(2):245–258. doi: 10.1016/j.ccc.2016.12.001

Table 1. PICS biomarkers.

Laboratory markers that are readily available in most clinical settings and can be used to identify patients with or at risk of PICS.

PICS	Measurement
Critically ill patient	Admission to the ICU > 14 days
Persistent inflammation	CRP > 50 μg/dL
Persistent immunosuppression	Total lymphocyte count < 0.80 ×10⁹/L
Catabolic state	Serum albumin < 3.0 g/dL Pre-albumin <10mg/dL Creatinine height index < 80% Weight loss > 10% ‘or’ BMI < 18 during hospitalization

Abbreviations: PICS – Persistent Inflammation, Immunosuppression and Catabolism Syndrome; ICU – Intensive Care Unit; CRP – C-reactive protein; BMI – Body mass index;