TABLE 2.
MICa analysis of Lactobacillus species strains grown in MRS broth
| Lactobacillus species strain | MICb of:
|
||||||||
|---|---|---|---|---|---|---|---|---|---|
| KAN | ERY | TET | CIP | CHLOR | NOV | CA | TCA | TDCA | |
| L. acidophilus ATCC 332 | 128 | 0.5 | 1 | >1,024 | 16 | 2 | 2,000 | ND | 16,000 |
| L. acidophilus ATCC 4356 | 512 | 0.125 ± (1)c | 2 ± (1) | 256 | 8 ± (1) | 0.5 | 2,000 | 32,000 | 16,000 |
| L. acidophilus ATCC 4357 | 256 | 32 ± (1) | 4 | 1,024 | 4 ± (2) | 0.5 ± (1) | 2,000 ± (1) | 512,000 | >256,000 |
| L. acidophilus ATCC 53103 | >512 | 4 | 2 | >1,024 | 16 | >32 | 2,000 | ND | 256,000 |
| L. acidophilus ATCC 53544 | 256 | 0.125 | 4 | 128 | 8 | >32 | 2,000 | 32,000 | ND |
| L. acidophilus PI KS-13 | 128 ± (2) | 0.125 | 4 | 256 ± (2) | 4 | 0.5 | 1,000 ± (1) | 16,000 | 1,000 |
| L. bifidus ATCC 11146 | 128 | 0.0625 | 2 | >1,024 | 4 | 32 | 2,000 | ND | 8,000 |
| L. crispatus JCM 5810 | 256 ± (1) | <0.03125 ± (2) | 1 ± (2) | 256 ± (2) | 4 ± (2) | 0.5 ± (2) | 1,000 ± (1) | 32,000 | 16,000 |
| L. delbrueckii ATCC 11842 | 256 ± (1) | <0.03125 | 1 | 128 ± (2) | 4 | 0.25 ± (1) | 500 ± (1) | 4,000 | 1,000 |
| L. delbrueckii DSM 20080 | 16 | <0.03125 | 1 | 128 | 2 | >32 | 500 | 1,000 | ND |
| L. fermentum ATCC 11976 | 16 | <0.03125 | 2 | 64 | 2 | 2 | 2,000 | 32,000 | ND |
| L. fermentum ATCC 23271 | 128 | 0.125 | 16 | 128 | 4 | 8 | 1,000 | 256,000 | ND |
| L. gasseri ATCC 19992 | >512 | 0.125 ± (1) | 4 | 512 ± (1) | 8 | 2 ± (1) | 1,000 ± (1) | 16,000 | 2,000 |
| L. gasseri NCK 99 | 512 | 0.125 | 4 | 512 | 4 | 4 | 1,000 | 8,000 | ND |
| L. johnsonii ATCC 33200 | 512 | 0.125 ± (2) | 16 | 512 ± (1) | 8 ± (1) | 2 ± (2) | 1,000 ± (1) | 16,000 | 16,000 |
| L. johnsonii PI 100-100 | 256 ± (2) | 0.125 ± (2) | 4 ± (1) | 512 ± (1) | 4 | 0.5 ± (2) | 1,000 ± (1) | 16,000 | 4,000 |
| L. maltaromicus BCCM 6903 | 256 | 64 | 32 | 512 | 4 | 1 | 4,000 | ND | 256,000 |
| L. paracasei ATCC 27092 | 512 | 2 ± (2) | 8 ± (1) | >1,024 | 16 ± (1) | >32 | 1,000 | 4,000 | 1,000 |
| L. paracasei JCM 1109 | 256 | 0.5 | 1 | >1,024 | 4 | 0.25 | 1,000 | ND | 64,000 |
| L. plantarum ATCC 14917 | >512 | 2 | 64 | >1,024 | 8 | 1 | 4,000 | ND | >256,000 |
| L. plantarum WCFS1 | >1,024 | 2 | 64 | >2,048 | 8 | 1 | 2,000 | 512,000 | ND |
| L. reuteri ATCC 23272 | 128 | 1 | 64 | 256 | 16 | 4 | 2,000 | 256,000 | ND |
| L. ruminis ATCC 25644 | >512 | 0.25 | 1 | >1,024 | 4 | 0.125 | 1,000 | ND | 256,000 |
| L. sake PI Lb5 | 128 | 2 | 2 | 128 | 8 | 32 | 16,000 | 512,000 | ND |
| L. sake PI Lb6 | 128 | 1 | 2 | 128 | 4 | 32 | 16,000 | 512,000 | ND |
| L. sake PI Lb15 | >512 | 1 | 128 | 512 | 16 | >32 | 4,000 | 512,000 | ND |
| L. vaginalis PI 675a | 128 | 0.5 | 16 | 1,024 | 4 | 32 | 1,000 | 32,000 | ND |
a
MICs are reported in micrograms per milliliter. ND, susceptibility not determined.
b
For drug name abbreviations; see Table 1, footnote b. NOV, novobiocin; CA, cholic acid; TCA, taurocholic acid; TDCA, taurodeoxycholic acid.
c
MIC measurements were repeated for many strains and revealed some slight differences. These are reported as ± the number of dilution differences that were observed.