Table. Baseline characteristics and incidence of cardiovascular events in AF patients over 6 and 12 months.
| Control | Intervention | |||
|---|---|---|---|---|
| Baseline characteristics | Median (IQR) unless indicated | |||
| List size | 7039 (4724, 10832) | 6803 (4071, 11368) | ||
| Prevalence of AF per 100 patients | 1.71 (1.11, 2.20) | 1.92 (1.77, 2.21) | ||
| Proportion of AF patients who are female | 44.6% (40.9, 50.0) | 46.3% (42.4, 50.0) | ||
| Proportion of AF patients under 80 years | 56.5% (51.0, 62.3) | 56.9% (51.6, 59.8) | ||
| Proportion eligible for OAC and prescribed OAC at baseline1 | 61.9% (9.89) | 63.5% (8.85) | ||
| Events | Incidence (patients with at least one event per 1000 AF patients) | P Value2 | ||
| Thromboembolic stroke, TIA or other major thromboembolism | N=23 | N=23 | ||
| 6 months | 0 (0, 7.75) | 10.3 (0, 16.3) | 0.03 | |
| 12 months | 12.6 (0, 22.3) | 14.5 (4.2, 26.1) | 0.41 | |
| Haemorrhage (including haemorrhagic stroke)3 | 6 months | 26.5 (15.0)1 | 21.0 (14.7)1 | 0.414 |
| 12 months | 50.3 (33.4, 57.3) | 34.7 (27.4, 43.6) | 0.054 | |
| All cause stroke3 | 6 months | 8.5 (0, 17.7) | 7.9 (0, 13.4) | 0.43 |
| 12 months | 24.8 (19.3, 28.9) | 15 (9.1, 28.3) | 0.06 | |
| Transient ischaemic attack | 6 months | 0 (0,0) | 6.4 (0, 12.2) | 0.008 |
| 12 months | 2.3 (0, 9.0) | 10.0 (4.2, 18.2) | 0.027 | |
| Thromboembolic stroke | 6 months | 0 (0, 0) | 0 (0, 4.1) | 0.40 |
| 12 months | 0 (0, 12.8) | 0 (0, 5.0) | 0.36 | |
| Haemorrhagic stroke3 | 6 months | 0 (0,0)1 | 0 (0,0)1 | 0.82 |
| 12 months | 0 (0, 0.96) | 0 (0, 3.14) | 0.92 | |
| Unspecified stroke | 6 months | 5.2 (0, 16.4) | 3.2 (0, 9.4) | 0.26 |
| 12 months | 17.0 (11.4)1 | 13.3 (11.0)1 | 0.394 | |
1
Mean (SD)
2
Mann Whitney U test
3
N=22 in the control arm for haemorrhagic event searches (see Figure). The other searches were unaffected.
4
P value obtained from weighted linear regression.