Table 6. The differentially expressed miRNAs (sepsis-induced AKI and sepsis-non AKI >1.5) and their predicted target genes.

microRNA	Fold change	Predicted oxidative stress associated target genes
miR-142-5p	0.423581	IGF2BP3, PIK3C2A, TNFAIP6, AKT1, IGF1, IL8, IL6, PPARGC1A, SIRT1, NOX5, OXSR1, MTOR, PDCD4, PIK3C2A
miR-23a-3p	0.394515	AKT2, PPARGC1A, SIRT1, OXSR1, MTOR, PIK3C2G, IL6R, TNFAIP6, PIK3C2A, FOXO4, PDCD4,IGF1, IL6
miR-22-3p	0.563722	AKT3, SIRT1, IL6R, PIK3CD, PPARGC1B, HIF1AN, PIK3CD, IGF1, PDCD2L, PIK3C2G, WNT1
miR-4456	0.647923	IGF2BP1, SIRT1, HIF3A, PPARGC1B, IL10RB
miR-191-5p	0.505111	OXSR1, FOXO1, PPARGC1A, PIK3C2B, PDCD5, PIK3R3
miR-4270	2.333464	AKT3, FOXO4, HIF1A, NOX1, NOX5, PIK3C3, PIK3R1, PPARGC1A, WNT1, PDCD1, IL10RA, IGF2BP1, SIRT5
miR-3165	1.500869	IGFBP6, IGFBP7, IL11RA,IL6ST, PPARGC1A, HIF3A, PIK3C2A
miR-4321	1.720649	AKT1, MTOR, NOX5, IL17RA, IL26