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. Author manuscript; available in PMC: 2017 Mar 15.
Published in final edited form as: Int J Anesthesiol Res. 2016 Aug 16;4(8):313–321. doi: 10.19070/2332-2780-1600065

Figure 4.

Figure 4

The mean values of the ranks for presurgical, PACU and POD 1 time points are shown. We grouped and plotted together (same line) subjects based on 3 ranges of DSF z score change (FIG 4). The sub-jects with the worst cognitive development (most negative DSB z score shift) were plotted with a blue solid line. The green dashed line showed the intermediate 33% in terms of DSB score changes. The best third (smallest decrease or actual increase) are shown as a red dotted line. The large gray circular symbols are the mean values of the cognitive rank. Examining all 3 cytokine values (presurgical, PACU and POD1) against a co-factor (the tertiary categorical of the change in DSF z score), we found: factor (time, visit) was highly sig-nificant (p=0.000). For IL8, there was a significant between subject effect (p=0.022) based on the DSF cate-gorical. A similar analysis for the DSB categorical showed significance for factor (p=0.001), primarily due to the quadratic component of contrast. There was also a significant between subject effect (p=0.004). (Using continuous variables for the z score change in DSF and DSB did not compromise the significance; p values were p=0.013 and 0.036 respectively.)