Table 2. Odds ratio analysis with odds ratios after adjustment for covariates (including age and gender) between the MetS and 16 SNPs in five selective circadian clock genes, which have nominal evidence of association (P < 0.01).

				Additive model			Dominant model			Recessive model
Gene	SNP	Alleles		OR	95% CI	P	OR	95% CI	P	OR	95% CI	P
ARNTL	rs10832020	C	T	1.23	1.05–1.45	0.0114	1.06	0.87–1.28	0.5586	1.54	1.13–2.09	0.0065
GSK3B	rs2199503	T	C	0.83	0.70–0.99	0.0331	1.04	0.85–1.26	0.7245	0.64	0.47–0.89	0.0070
PER3	rs10746473	G	A	1.20	1.04–1.38	0.0116	1.46	1.17–1.83	0.0010	1.11	0.88–1.40	0.3691
	rs2797685	C	T	1.17	1.01–1.35	0.0314	1.41	1.11–1.78	0.0047	1.07	0.85–1.33	0.5731
	rs1689904	C	T	1.16	1.01–1.34	0.0352	1.39	1.10–1.76	0.0061	1.07	0.86–1.33	0.5618
	rs1773138	T	C	0.85	0.74–0.99	0.0304	0.94	0.76–1.17	0.5902	0.71	0.56–0.90	0.0043
RORA	rs17237367	A	G	0.82	0.68–0.98	0.0263	0.75	0.62–0.91	0.0036	0.74	0.53–1.05	0.0926
	rs58469372	A	G	0.82	0.71–0.95	0.0092	0.85	0.70–1.04	0.1113	0.71	0.54–0.93	0.0129
	rs12591650	A	G	1.20	1.04–1.38	0.0109	1.39	1.11–1.75	0.0049	1.16	0.93–1.44	0.1948
	rs12594188	C	T	1.21	1.01–1.45	0.0389	1.33	1.10–1.61	0.0035	1.32	0.92–1.88	0.1272
	rs17270446	G	C	0.97	0.70–1.35	0.8455	1.37	1.12–1.68	0.0021	0.84	0.44–1.63	0.6109
	rs11630062	C	T	0.92	0.80–1.05	0.2267	0.76	0.62–0.93	0.0082	1.02	0.80–1.30	0.8834
	rs8029848	G	A	1.28	1.05–1.56	0.0127	1.41	1.17–1.71	0.0004	1.43	0.98–2.09	0.0629
	rs8034880	G	A	1.29	1.05–1.58	0.0150	1.44	1.19–1.74	0.0002	1.44	0.97–2.14	0.0711
	rs72752802	C	A	0.81	0.69–0.94	0.0053	0.87	0.72–1.06	0.1716	0.67	0.50–0.88	0.0045
RORB	rs972902	A	G	0.72	0.55–0.96	0.0227	0.76	0.62–0.93	0.0087	0.57	0.33–0.98	0.0426

CI = confidence interval, MetS = metabolic syndrome, OR = odds ratio. Analysis was obtained after adjustment for covariates including age and gender. P values of < 0.01 are shown in bold.