Table 2. The inhibitory effect of T521 on the proliferation of various cell lines.
Cell lines | Tissue type | IC50(μM) |
---|---|---|
Tumor | ||
MCF-7 | Breast | 1.58 |
HepG2 | Liver | 3.17 |
Bel7402 | Liver | 5.13 |
MG63 | Bone | 6.25 |
SaOS-2 | Bone | 1.56 |
U-2OS | Bone | 1.06 |
SH-SY5Y | Brain | 1.37 |
HeLa | Cervix | 4.43 |
HCT-116 | Colon | 3.55 |
HT29 | Colon | 3.86 |
PC3 | Prostate | 1.09 |
A549 | Lung | 3.56 |
Normal | ||
MRC-5 | Lung | 2.64 |
HEK-293 | Kidney | 8.66 |
L02 | Liver | 7.11 |