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. 2016 Aug 17;8(1):248–267. doi: 10.18632/oncotarget.11335

Figure 7. QC caused apoptosis in MCF-10A-Tr cells implanted xenograft mice by induction of DR5.

Figure 7

(A) i) Change in body weight of mice treated with QC, TRAIL and their combination. ii) Change in tumor volume of QC, TRAIL and TRAIL+QC treated mice. (B) Expression of Ki-67. (C) H&E staining of the mice breast fat pad tissue section (scale bar 10 μm). (D) IHC i) DR5 ii) Ki-67 (scale bar 10 μm; arrows indicate DR5/Ki-67 expression). (E) Expression of CASPASE (S), DR5 and p53 in tumor lysate. Images shown are representative of three different experiments. Data are the mean ± SD of three independent experiments.