Table 4. Diagnostic values of selected genes for esophageal cancer using different models.
Gene | No. of sample | Model A | Model B | Model C | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Cases | Controls | AUC | 95% CI | P | AUC | 95% CI | P | AUC | 95% CI | P | |
APC | 43 | 10 | 0.73 | 0.535-0.925 | 0.024 | – | – | – | – | – | – |
BNIP3 | 43 | 10 | 0.556 | 0.388-0.723 | 0.585 | 0.856 | 0.749-0.962 | 0.001 | 0.876 | 0.775-0.978 | < 0.001 |
BRCA1 | 43 | 10 | 0.326 | 0.180-0.471 | 0.088 | 0.13 | 0.033–0.228 | < 0.001 | 0.712 | 0.529–0.895 | 0.039 |
CCND1 | 43 | 10 | 0.521 | 0.301–0.741 | 0.838 | 0.799 | 0.648–0.949 | 0.003 | 0.817 | 0.667–0.966 | 0.002 |
CDKN2A | 43 | 10 | 0.437 | 0.290–0.585 | 0.539 | 0.451 | 0.301–0.601 | 0.633 | 0.912 | 0.832–0.992 | < 0.001 |
HTATIP2 | 43 | 10 | 0.698 | 0.558–0.837 | 0.053 | 0.872 | 0.766–0.978 | < 0.001 | 0.881 | 0.779–0.983 | < 0.001 |
ITGAV | 43 | 10 | 0.779 | 0.651–0.907 | 0.006 | 0.879 | 0.783–0.975 | < 0.001 | 0.898 | 0.807–0.988 | < 0.001 |
NFKB1 | 43 | 10 | 0.605 | 0.430–0.779 | 0.306 | 0.855 | 0.753–0.956 | 0.001 | 0.869 | 0.772–0.966 | < 0.001 |
PIK3R1 | 43 | 10 | 0.635 | 0.464–0.806 | 0.187 | 0.93 | 0.863–0.998 | < 0.001 | 0.969 | 0.928–1.000 | < 0.001 |
PRDM16 | 43 | 10 | 0.958 | 0.906–1.000 | < 0.001 | 0.967 | 0.921–1.000 | < 0.001 | 0.988 | 0.965–1.000 | < 0.001 |
PTEN | 43 | 10 | 0.663 | 0.491–0.835 | 0.112 | 0.66 | 0.491–0.830 | 0.117 | 0.675 | 0.505–0.845 | 0.088 |
PTX3 | 43 | 10 | 0.593 | 0.430–0.756 | 0.363 | 0.737 | 0.604–0.871 | 0.02 | 0.749 | 0.617–0.880 | 0.015 |
RASSF1 | 43 | 10 | 0.681 | 0.528–0.835 | 0.076 | 0.66 | 0.488–0.833 | 0.117 | 0.676 | 0.502–0.850 | 0.086 |
SOCS1 | 43 | 10 | 0.628 | 0.472–0.784 | 0.211 | 0.74 | 0.600–0.897 | 0.019 | 0.752 | 0.615–0.890 | 0.014 |
TAP2 | 43 | 10 | 0.14 | 0.031–0.248 | < 0.001 | 0.028 | 0.000–0.066 | < 0.001 | – | – | – |