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. 2016 Nov 22;8(1):679–691. doi: 10.18632/oncotarget.13510

Table 4. Diagnostic values of selected genes for esophageal cancer using different models.

Gene No. of sample Model A Model B Model C
Cases Controls AUC 95% CI P AUC 95% CI P AUC 95% CI P
APC 43 10 0.73 0.535-0.925 0.024
BNIP3 43 10 0.556 0.388-0.723 0.585 0.856 0.749-0.962 0.001 0.876 0.775-0.978 < 0.001
BRCA1 43 10 0.326 0.180-0.471 0.088 0.13 0.033–0.228 < 0.001 0.712 0.529–0.895 0.039
CCND1 43 10 0.521 0.301–0.741 0.838 0.799 0.648–0.949 0.003 0.817 0.667–0.966 0.002
CDKN2A 43 10 0.437 0.290–0.585 0.539 0.451 0.301–0.601 0.633 0.912 0.832–0.992 < 0.001
HTATIP2 43 10 0.698 0.558–0.837 0.053 0.872 0.766–0.978 < 0.001 0.881 0.779–0.983 < 0.001
ITGAV 43 10 0.779 0.651–0.907 0.006 0.879 0.783–0.975 < 0.001 0.898 0.807–0.988 < 0.001
NFKB1 43 10 0.605 0.430–0.779 0.306 0.855 0.753–0.956 0.001 0.869 0.772–0.966 < 0.001
PIK3R1 43 10 0.635 0.464–0.806 0.187 0.93 0.863–0.998 < 0.001 0.969 0.928–1.000 < 0.001
PRDM16 43 10 0.958 0.906–1.000 < 0.001 0.967 0.921–1.000 < 0.001 0.988 0.965–1.000 < 0.001
PTEN 43 10 0.663 0.491–0.835 0.112 0.66 0.491–0.830 0.117 0.675 0.505–0.845 0.088
PTX3 43 10 0.593 0.430–0.756 0.363 0.737 0.604–0.871 0.02 0.749 0.617–0.880 0.015
RASSF1 43 10 0.681 0.528–0.835 0.076 0.66 0.488–0.833 0.117 0.676 0.502–0.850 0.086
SOCS1 43 10 0.628 0.472–0.784 0.211 0.74 0.600–0.897 0.019 0.752 0.615–0.890 0.014
TAP2 43 10 0.14 0.031–0.248 < 0.001 0.028 0.000–0.066 < 0.001