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. 2016 Nov 23;8(1):705–721. doi: 10.18632/oncotarget.13525

Figure 10. miR-206 downregulates A3AR expression in mouse colon.

Figure 10

(A) miR-206 expression was higher in DSS-colitis mice than in control mice, and was upregulated and downregulated in the colon of agomir- and antagomir-treated mice, respectively, as compared with corresponding NC levels. (B, C) A3AR mRNA and protein expression was significantly decreased in DSS-colitis mice, and was significantly downregulated and upregulated after miR-206 agomir and antagomir treatment, respectively (relative to corresponding NC levels). (D) Representative western blotting showing A3AR expression following various treatments. Results are presented as means ± SD. *P < 0.05 and **P < 0.01, compared with normal group; #P < 0.05 and ##P < 0.01, compared with corresponding NC group.