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. 2016 Nov 23;8(1):705–721. doi: 10.18632/oncotarget.13525

Figure 8. Reversal of miR-206-inhibitory effect by A3AR-siRNA.

Figure 8

(A, B) Relative to siRNA-NC transfection, A3AR-siRNA transfection abrogated the miR-206-inhibitor effect on nuclear and cytoplasmic NF-κB p65 expression in TNF-α-treated cells. (C, D) Representative western blots showing NF-κB p65 expression in the indicated groups. (E–H) Relative to siRNA-NC transfection, A3AR-siRNA transfection alleviated the miR-206-inhibitor effect on IL-8/IL-1β mRNA expression and secretion in TNF-α-treated cells. Results are expressed as fold-change relative to the corresponding NC and presented as means ± SD of 3 independent experiments. *P < 0.05; **P < 0.01.