. 2016 Nov 23;8(1):954–966. doi: 10.18632/oncotarget.13512

Table 1. Relationships between clinicopathological characteristics and the expression of p53, COX2, EGFR and nm23.

Clinical parameter		EGFR expression level				COX2 expression level				p53 expression level				nm23 expression level
		Low	High	χ²	P	Low	High	χ²	P	Low	High	χ²	P	Low	High	χ²	P
Age(Years)	<60	121	139	0.004	0.948	41	219	0.008	0.928	101	158	1.521	0.218	93	167	2.487	0.115
	≥60	92	107			32	167			89	110			57	141
Gender	female	76	113	4.956	0.026	24	165	2.469	0.116	76	112	0.147	0.701	62	127	0.000	0.984
	male	137	133			49	221			114	156			88	181
BMI	<25	129	108	0.003	0.958	22	215	0.475	0.491	98	139	0.103	0.748	88	148	0.267	0.605
	≥25	46	38			10	74			36	47			34	50
pathology grading	I-II	121	125	1.649	0.199	42	204	0.542	0.462	113	133	4.336	0.037	81	165	0.007	0.931
	III-IV	92	121			31	182			77	135			69	143
Tumor size(cm)	<8cm	109	124	0.014	0.905	42	191	1.542	0.214	96	136	0.000	0.992	73	160	0.351	0.554
	≥8cm	104	121			31	194			93	132			76	148
Lymphatic metastasis	No	101	103	1.162	0.281	35	169	0.707	0.400	87	116	0.262	0.608	67	136	0.038	0.845
	Yes	112	140			36	216			102	150			81	171
TNM stage	I-II	104	86	9.049	0.003	35	155	1.536	0.215	85	105	1.415	0.234	59	130	0.344	0.558
	III-IV	109	160			38	231			105	163			91	178

lack of partial data