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. 2017 Mar 9;10:1503–1512. doi: 10.2147/OTT.S130139

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© 2017 Chen et al. This work is published and licensed by Dove Medical Press Limited

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Trim59 inhibits cell apoptosis and promotes cell proliferation of Bca cell lines.

Notes: (A) Flow cytometry analysis showed that cell apoptosis rates increased significantly after the transfection of si-Trim59. (B) si-Trim59 transfection of T24 and NC cells did not contribute to the cell cycle arrest compared with NC. Knockdown of Trim59 did not increased G1 phase percentage of T24 and 5637 cells. (C) Cell proliferation by CCK-8 assay and colony formation experiments. The proliferation capacity of T24 and 5637 cells was significantly inhibited by the downregulation of Trim59. The colony number of T24 and 5637 cells with si-Trim59 transfection decreased significantly compared with NC.

Abbreviations: Bca, bladder cancer; CCK-8, cell counting kit-8; NC, negative control; SD, standard deviation; si-Trim59, small interfering-Trim59.

Trim59 inhibits cell apoptosis and promotes cell proliferation of Bca cell lines.

Notes: (A) Flow cytometry analysis showed that cell apoptosis rates increased significantly after the transfection of si-Trim59. (B) si-Trim59 transfection of T24 and NC cells did not contribute to the cell cycle arrest compared with NC. Knockdown of Trim59 did not increased G1 phase percentage of T24 and 5637 cells. (C) Cell proliferation by CCK-8 assay and colony formation experiments. The proliferation capacity of T24 and 5637 cells was significantly inhibited by the downregulation of Trim59. The colony number of T24 and 5637 cells with si-Trim59 transfection decreased significantly compared with NC.

Abbreviations: Bca, bladder cancer; CCK-8, cell counting kit-8; NC, negative control; SD, standard deviation; si-Trim59, small interfering-Trim59.