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3D response surface plots for the effect of the independent variables on Y1 (left side) and Y2 (right side).
Note: Units of measure for X1, X2 and X3 are (%), Y1 (nm) and Y2 (%).
Abbreviations: Y1, particle size; Y2, entrapment efficiency; X1, PLGA in organic phase; X2, organic in aqueous phase; X3, PVA in aqueous phase; PLGA, poly(lactide-co-glycolide); PVA, poly (vinyl alcohol).
