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(A) Cytotoxicity of drug-loaded LPNPs against KB cells after incubation for 48 h (n=4). (B) Plot of the CI as the function of cell viability for KB cells treated with drug-loaded LPNPs. P-values were calculated by the Student’s t-test: *P<0.05.
Abbreviations: CI, combination index; DOX, doxorubicin; LPNPs, lipid–polymer hybrid nanoparticles; TPL, triptolide.
