Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Characterization of drug-loaded LPNPs
| Samples | Size (nm) | PDI | EE (%) | LE (%) | Zeta potential (mV) |
|---|---|---|---|---|---|
| DOX-LPNPs | 111±7 | 0.10±0.03 | 80.2±0.3 | 6.2±0.5 | −5.4±0.5 |
| TPL-LPNPs | 108±6 | 0.09±0.03 | 71.3±0.4 | 2.9±0.3 | −15.7±1.5 |
| DOX/TPL-1/0.2 | 120±5 | 0.12±0.04 | 75.5±0.5 (DOX) | 5.3±0.3 (DOX) | −9.7±0.8 |
| 58.3±0.4 (TPL) | 1.1±0.1 (TPL) |
Abbreviations: DOX, doxorubicin; EE, encapsulation efficiency; LE, loading efficiency; LPNPs, lipid–polymer hybrid nanoparticles; PDI, polydispersity index; TPL, triptolide.
