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. 2016 Jun 6;8(5):7489–7501. doi: 10.18632/oncotarget.9841

Figure 2. Ectopic HDAC8 expression showed a high correlation with AHR in hepatocellular carcinoma (HCC).

Figure 2

A. Overexpression of HDAC8 protein was detected in HCC patients with high AHR mRNA expression. B. The expression pattern of HDAC8 showed significant co-localization with AHR in tumor cells of HCC patients. HDAC8, red; AHR, green. C. High levels of HDAC8 mRNA were detected in HCC patients exhibiting high AHR mRNA expression. D. High AHR expression coupled with high proto-oncogenes (CCND1 and E2F1) expression but with lower tumor suppressor gene (p53 and RB1) expression in HCC patients. a, six samples from the high AHR group could not be detected.