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. 2016 Dec 7;8(5):7598–7613. doi: 10.18632/oncotarget.13814

Figure 4. Effect of OTX015 on the expression of cancer stem cell markers in TNBC cell models.

Figure 4

Cells were exposed for 24, 48 and 72 h to OTX015 (650 nM for HCC1937 - ■ - and MDA-MB-468 - ■ -, and 75 nM for MDA-MB-231 cells - ■ -) and expression of stemness-related genes was determined by qRT-PCR. Differences in the mRNA levels of OTX015-treated cells vs. controls were determined by a one-way ANOVA test (p < 0.01) followed by an SNK a posteriori test (*p < 0.05, **p < 0.01). Bars and vertical lines represent the mean ± SEM, respectively (n = 3).