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. 2016 Dec 9;8(5):7710–7721. doi: 10.18632/oncotarget.13846

Figure 5. The overexpression of STAT3 enhances the proliferation potential of ICC cells.

Figure 5

(A) Proliferation of STAT3 overexpressed RBE cells was evaluated by a CCK8 assay in indicated time points. *P < 0.05, compared with negative control group. (B) The volumes of the subcutaneous tumors developed from RBE cells were significantly increased by STAT3 overexpression. N = 3 for each group. **P < 0.01, compared with negative control group. (C) The phosphorylation of STAT3 was detected 72 h after STAT3 overexpression in RBE and HUCCT1 cells, respectively.