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. 2016 Dec 10;8(5):7729–7739. doi: 10.18632/oncotarget.13890

Figure 5. Silencing of Bcl-2/Twist1 inhibited growth of Tca8113 xenograft tumor in the mouth floor in vivo.

Figure 5

(A) and (B) Exhaustion of Bcl-2/Twist1 inhibited tumor growth, p = 0.001. (C) In the control group, 2 of 24 lymph nodes had tumor metastasis whereas 20 lymph nodes of in the sh-Bcl-2 group and 16 in both the sh-Twist1 and sh-Bcl-2/Twist1 groups were negative. (D) HE staining was used to examine lymph node metastasis. (E) Immunohistochemical staining of Bcl-2, Twist1, E-cadherin, N-cadherin, Vimentin, and MMP2/9 in murine tumors.