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. 2016 Dec 16;8(5):7827–7838. doi: 10.18632/oncotarget.13974

Figure 2. Rottlerin induced cell cycle arrest and inhibited cell migration and invasion on NSCLC.

Figure 2

(A) Cell cycle was analyzed by Fow cytometry. Rottlerin induced NSCLC cell cycle arrest. (B) The inhibitory effect of rottlerin on NSCLC migration was detected using wound healing assay in A549 cells. Right panel, Quantitative results are illustrated for left panels. *P < 0.05, vs control group (DMSO treatment). (C) Top panel, the inhibitory effect of rottlerin on NSCLC invasion was detected by Transwell chambers assay. Bottom panels, Quantitative results are illustrated for Top panel. *P < 0.05, **< 0.01 vs control.