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. 2016 Dec 16;8(5):7827–7838. doi: 10.18632/oncotarget.13974

Figure 5. Down-regulation of TAZ by its siRNA promoted rottlerin-induced TAZ inhibition.

Figure 5

(A) Top panel: The expression of TAZ and β-catenin was detected by Western blotting in NSCLC with TAZ cDNA transfection and rottlerin treatment. Bottom panels, Quantitative results are illustrated for Top panel.*P < 0.05, **< 0.01 vs control. #p < 0.05 compared with rottlerin treatment or TAZ cDNA transfection. Control: pcDNA3.1 transfection; cDNA : TAZ cDNA; Both : TAZ cDNA + rottlerin. (B) Top panel: The expression of TAZ was detected by Western blotting in NSCLC with TAZ siRNA transfection and rottlerin treatment. Bottom panels, Quantitative results are illustrated for Top panel.*P < 0.05, **< 0.01 vs control. #p < 0.05 compared with rottlerin treatment or TAZ siRNA transfection. Control: control siRNA; siRNA : TAZ siRNA; both : TAZ siRNA + rottlerin.