TABLE 4.
Sensitivity relative to BAL fluid culture positivity for Aspergillus speciesa
Test | BAL fluid culture positive
|
BAL fluid culture negative
|
P valueb | ||||
---|---|---|---|---|---|---|---|
No. | Sensitivity (%) | 95% CI | No. | Sensitivity (%) | 95% CI | ||
GM EIA with index of 0.5 | 27 | 89 | 71-98 | 22 | 59 | 36-79 | 0.02 |
GM EIA with index of 1.0 | 27 | 78 | 58-91 | 22 | 41 | 21-64 | 0.02 |
qPCR | 24 | 96 | 79-100 | 22 | 36 | 17-59 | <0.001 |
qPCR or GM EIA with index of 0.5 | 23 | 100 | 85-100 | 22 | 64 | 41-83 | 0.001 |
Among patients with proven or probable aspergillosis.
P value from Fisher's exact test comparing sensitivities between patients with BAL fluid cultures that revealed growth of Aspergillus species (positive) and those with culture-negative BAL fluid cultures.