Table 1. Clinicopathological characteristics of 16 CSCNETs.

Case	Reviewed Diagnosis	Age(year)	Tumor size(cm)	FIGOstage	Treatment	Metastasis	LVI	LNmetastasis	Follow up(months)	Clinicaloutcome	IHC
											Ki-67(%)	CgA	Syn	ERBB4
1	smcc	51	1.4×2.0	IB1	OP	brain	No	No	34	Died	5	+	+	+++
2*	smcc	45	2.5×1.0	IB1	OP	No	Yes	No	9	Alive	57.9	+	+	+++
3	smcc	39	2.5×2.5	IV	No OP	Vertebra	Yes	No	9	Died	90	-	+	+
4	smcc	40	3.5×3.2	III	No OP	No	Yes	Yes	101	Alive	63.5	-	+	+
5	smcc	51	2×1.8	IB1	OP, CTx	No	Yes	Yes	166	Alive	1	-	+	+
6	smcc,AIS withintestinal metaplasia	51	1.2×0.6	IB1	OP, CTx	No	Yes	No	160	Alive	47.5	+	+	+
7	smcc	28	1.0×0.36	IB1	OP, CTx	No	No	Yes	152	Alive	0	+	+	++
8	smcc	37	2.3×1.5	IB1	OP, CTx	Lung	Yes	Yes	11	Died	1.6	+	+	++
9	smcc	47	5.3×2.7	IB2	OP, CTx	No	Yes	Yes	59	Alive	72.5	+	+	+++
10*	smcc	46	1.2×0.8	IB1	OP, CTx,RTx	No	Yes	No	12	Alive	50.1	+	+	+++
11*	smcc	35	1.5×1.5	IB1	OP, CTx	No	Yes	No	30	Died	79.6	+	+	+++
12	smcc+rosette	45	2.0×2.2	IB1	OP	Lung, pancreas, bone	Yes	No	60	Alive	41.3	+	+	++
13*	smcc+rosette	48	4.5×1.6	IIA	OP	No	Yes	Yes	100	Alive	35	-	+	++
14	smcc	47	1.5×1.5	IB1	OP	no	Yes	No	60	Alive	67.8	+	+	++
15	smcc+rosette	47	1×1.5	IV	No OP,CTx, RTx	Bone, liver	Yes	Yes	29	Died	60	+	+	++
16*	smcc	33	2.1×1.0	IV	No OP,CTx, RTx	Lung	Yes	No	17	Alive	1	+	+	++

Abbreviations: *Normal and tumor tissues analyzed via WES; CNET: small cell neuroendocrine tumor; FIGO: Fédération Internationale de Gynécologieetd’ Obstétrique; LVI: lymphovascular invasion; LN: lymph node; IHC: immunohistochemistry; CgA: chromogranin A; Syn: synaptophysin; OP: radical hysterectomy; CTx: chemotherapy; RTx: radiotherapy.