Table 1. Clinicopathological characteristics of EOC patients in the training and validation cohort.
| Characteristic | All patients (n =10692) | Training cohort (n = 7021) | Validation cohort (n = 3671) | P |
|---|---|---|---|---|
| Age at diagnosis, years | 0.63 | |||
| Median (IQR) | 57(49-66) | 57(49-66) | 57(49-66) | |
| Year of diagnosis | 0.56 | |||
| 2004-2007 | 3936 | 2559 | 1377 | |
| 2007-2010 | 3261 | 2152 | 1109 | |
| 2010-2013 | 3495 | 2310 | 1185 | |
| Race | 0.17 | |||
| White | 9045 | 5906 | 3139 | |
| Black | 521 | 354 | 167 | |
| Other* | 1126 | 761 | 365 | |
| Marital status | 0.04 | |||
| Married | 6069 | 4042 | 2027 | |
| Single | 2085 | 1360 | 725 | |
| Others# | 2538 | 1619 | 919 | |
| FIGO Stage | 0.78 | |||
| I | 4172 | 2745 | 1427 | |
| II | 1445 | 937 | 508 | |
| III | 5075 | 3339 | 1736 | |
| Grade | 0.13 | |||
| Well differentiate | 1592 | 1051 | 541 | |
| Moderately differentiate | 2482 | 1581 | 901 | |
| Poor differentiate | 4482 | 2979 | 1503 | |
| Tumor location | ||||
| One site | 6738 | 4427 | 2311 | 0.87 |
| Bilateral site | 3859 | 2534 | 1325 | |
| Paired site | 95 | 60 | 35 | |
| Radiation | ||||
| No | 10565 | 6935 | 3630 | 0.70 |
| Yes | 127 | 86 | 41 | |
| Histology | 0.98 | |||
| Serous | 6037 | 3977 | 2060 | |
| Mucinous | 1022 | 669 | 353 | |
| Endometrioid | 2518 | 1642 | 876 | |
| Clear cell | 1054 | 692 | 362 | |
| Undifferentiated | 61 | 41 | 20 | |
| RLNs | 0.76 | |||
| Mean (range) | 14.37(1-90) | 14.45(1-90) | 14.23(1-90) | |
| PLNs | 0.77 | |||
| Mean (range) | 1.35(0-90) | 1.39(0-90) | 1.26(0-57) | |
| LNR | 0.72 | |||
| Mean (range) | 0.13(0.00-1.00) | 0.13(0.00-1.00) | 0.13(1.00-1.00) | |
| LODDS | 0.86 | |||
| Mean (range) | −0.99(-2.26-2.26) | −0.98(-2.26-2.26) | −0.99(-2.16-1.95) |
*
Other including American Indian/AK Native, Asian/Pacific Islander.
#
Other including Widowed, Divorced, Separated and unknown
Poor differentiate including Poor differentiate and undifferentiated
Abbreviations: RLNs, the number of lymph node examined; PLNs, the number of positive lymph node; LNR, positive lymph node ratio; LODDS, log of odds between the number of PLNs and number of negative nodes.