Figure 2.

Patient n. 64: T2-weighted images in axial A and sagittal C plane before B and after treatment D. The morphologic images (A and C) before CRT, showed heterogeneous irregular thickening along the rectal wall spreading into the perirectal fat (A, arrowheads). After CRT, a hypointense area relating to rectal wall thickening is still visible (B and D, arrowheads). Median Time intensity curve of volume of interest (E and G), segmented by expert radiologist, before treatment is shown in F and after treatment in H. These curves showed different contrast enhancement, with a ΔSIS of 31.93% classifying the patient as responder.