Table 1. Patient Characteristics and Clinical Staging.

Characteristics	All patients n=75 (%)	TRG 1–2 n= 55	TRG 3–4 n=20	p*
Gender				>0.05
Male/Female	50(67)/25(33)	37/18	13/7
Median age (range)	62(44-77)	62(44-77)	63(44-76)
Gunderson Risk (25)				>0.05
Intermediate: T3N0	4(5.3)	3	1
Moderately high: T3N1, T4N0	26 (34.7)	17	9
High: T3N2, T4N1-2	45 (60.0)	33	12
Distance from the anal verge				>0.05
≤ 5 cm	37(49)	28	9
> 5 cm	38(51)	27	11
Circumferential resection margin				>0.05
> 2 mm	32(43)	26	2
>1 and ≤ 2 mm	9(12)	7	2
≤ 1 mm	30(40)	20	10
Not mesurable	4(5)	2	2

^*Chi-square test or Mann- Whitney U Test