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. 2016 Dec 24;8(5):8173–8188. doi: 10.18632/oncotarget.14132

Figure 8. Mechanism of the HNE-induced alteration of mitochondrial membrane potential (MMP) in nutrient-deprived cancer cells.

Figure 8

Left: Cancer cells in glucose medium with or without glutamine. Right: Cancer cells in glutamine medium. In red are pathways leading to a reduction of MMP, in blue MMP increasing pathways. Thick lines indicate pathway activation. Dashed lines indicate the effects of the inhibitors DEAB and etomoxir.