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A. Consensus values heatmap, demonstrating a clearly delineated block structure for k=3, supporting a three-cluster solution; B. This is endorsed by the cumulative distribution function (CDF) curve, which approaches an ideal step function for k=3; C. The relative change in area under CDF curve illustrates that as k is increasing beyond k=3, there is a significant drop in the relative change in area under CDF curve, indicating an optimum at k=3.
