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. 2016 Dec 24;8(5):8294–8304. doi: 10.18632/oncotarget.14166

Table 2. Description of PET features.

PET Feature Explanation
Correlation A measure of continuous areas of same or similar voxel values in an image. An image with high correlation values is usually associated with large areas of similar uptake intensities.
Coarseness A measure of the intensity differences throughout the image.
COV A normalized measure of dispersion of a frequency distribution (standard deviation divided by the mean value of the activity concentration in the tumor volume).
Contrast A measure of local variations present in the image. A high contrast value indicates a high degree of local variation.
Complexity Measures the uniformity of patterns versus rate of change in an image.
Entropy Measures randomness of distribution, e.g. a homogenous matrix demonstrates low entropy.
Size Variation Measures the difference of the grey value when going to the next voxel. It is high when the intensity changes very often between single voxels.
Intensity Variation The intensity variation describes the variation of the intensity of different substructures.
Short Run Emphasis Measure of consecutive pixels which have the same gray level intensity along a specific linear orientation. Fine textures tend to contain more short runs with similar gray level intensities.
Long Run Emphasis Measure of consecutive pixels which have the same gray level intensity along a specific linear orientation. Coarse textures have more long runs with significantly different gray level intensities
Short Zone Emphasis Measures the distribution of short zones as the difference of the grey value when going to the next voxel. It is high when the intensity changes very often between single voxels.
Long Zone Emphasis Measures the distribution of long zones as the difference of the grey value when going to the next voxel.
Zone Percentage Measures the percentage of zones of a given size.
SUV Mean A measure of mean radiotracer accumulation in tumor lesions.
SUV Max A measure of maximum radiotracer accumulation in tumor lesions.
TNR Mean Mean tracer uptake in the tumor divided by that in normally appearing brain tissue.
TNR Max Maximal tracer uptake in the tumor divided by that in normally appearing brain tissue.
TLU The total lesion volume and its metabolic activity
Volume The total lesion volume