Table 2. Allele frequencies in cases and controls and odds ratio estimates for drug addiction.

SNP ID	Gene	Band	Alleles Aa/B	MAF		HWE p-value	ORs	95% CI	p-value
				Case	Control
rs886205	ALDH2	12q24.12	A/G	0.118	0.140	0.084	0.825	0.661-1.031	0.091
rs2238152	ALDH2	12q24.12	T/G	0.278	0.282	0.024#	0.980	0.830-1.157	0.813
rs4648328	ALDH2	12q24.12	T/C	0.277	0.285	0.041#	0.963	0.817-1.136	0.658
rs441	ALDH2	12q24.12	C/T	0.277	0.284	0.052	0.966	0.819-1.141	0.689
rs4646778	ALDH2	12q24.12	A/C	0.278	0.284	0.051	0.970	0.822-1.145	0.720
rs671	ALDH2	12q24.12	A/G	0.190	0.131	0.619	1.551	1.263-1.903	< 0.001*
rs11066028	ALDH2	12q24.12	A/C	0.095	0.094	0.501	1.013	0.785-1.036	0.922
rs7296651	ALDH2	12q24.12	C/G	0.121	0.144	0.021#	0.814	0.653-1.014	0.066

MAF, minor allelic frequency; HWE, Hardy-Weinberg Equilibrium; ORs, odds ratios; CI: confidence interval.

^aMinor allele;

^#HWE p-value ≤ 0.05 was excluded;

^*p value ≤ 0.05.

Bonferroni's multiple adjustment was applied, with p<0.00125 (0.05/40).