Table 5. ALDH2 haplotype frequencies and the association with drug addiction risk.
| Block ID | Haplotype | Freq(case) | Freq(control) | χ2 | Pearson's p | OR | 95% CI | p-adj | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | ATCGA | 0.095 | 0.091 | 0.128 | 0.7201 | 0.999 | 0.756 | 1.320 | 0.996 |
| GTCAC | 0.190 | 0.129 | 19.65 | < 0.001* | 1.668 | 1.328 | 2.094 | < 0.001* | |
| GCAGC | 0.278 | 0.283 | 0.101 | 0.7511 | 1.003 | 0.836 | 1.202 | 0.977 | |
| ATCGC | 0.024 | 0.049 | 12.76 | < 0.001* | 0.444 | 0.281 | 0.704 | < 0.001* | |
| GTCGC | 0.414 | 0.445 | 2.726 | 0.0987 | 0.859 | 0.731 | 1.009 | 0.065 | |
OR: odd ratio; CI: confidence interval.
p-adj: p-value was adjusted by sex and age;
p value ≤ 0.05; Bonferroni's multiple adjustment was applied, with p<0.00125.