Table 2. HPT-axis hormone concentrations and prevalence of low T3 syndrome as a function of histological diagnosis of brain tumor A.
| Brain tumor histological diagnosis | F (p) or | X2 (p) | ||||||
|---|---|---|---|---|---|---|---|---|
| High grade glioma | Low grade glioma | Meningioma | Pituitary adenoma | Acoustic neuroma | Other | |||
| TSH (μIU/ml) | .62 (.74) | 1.24 (.82) | .63 (1.08) | .93 (1.23) | .45 (1.07) | .69 (.93) | 6.86 (.231) | - |
| Free triiodothyronine (pg/ml) | 1.48 (.53) | 1.51 (.61) | 1.54 (.73) | 1.97 (.74) | 1.90 (.92) | 1.38 (.74) | 26.14 (<.001) | - |
| Total triiodothyronine (ng/dl) | 57.93 (23.01) | 73.19 (24.31) | 66.44 (22.80) | 83.41 (26.11) | 78.42 (29.41) | 62.97 (30.02) | 28.29 (<.001) | - |
| Free thyroxine (pg/ml) | 11.00 (4.04) | 9.92 (3.89) | 10.52 (4.83) | 9.14 (4.45) | 11.53 (4.27) | 10.84 (4.60) | 12.95 (.024) | - |
| Total thyroxine (μg/dl) | 6.60 (2.10) | 6.60 (1.95) | 7.05 (2.57) | 6.30 (2.10) | 7.75 (3.62) | 7.00 (1.80) | 8.11 (.15) | - |
| Reversed triiodothyronine (ng/ml) | .49 (.25) | .42 (.17) | .46 (.25) | .26 (.15) | .37 (.26) | .45 (.46) | 42.78 (<.001) | - |
| Low free triiodothyronine concentrations (<2 pg/ml) | 43 (88%) | 18 (86%) | 69 (74%) | 19 (53%) | 7 (50%) | 14 (88%) | - | 20.57 (.001) |
| Low total triiodothyronine concentrations (<70 ng/dl) | 30 (61%) | 9 (43%) | 54 (58%) | 8 (22%) | 5 (36%) | 9 (60%) | - | 18.16 (.003) |
A Kruskal Wallis test for continuous variables and Pearson Chi-squared test for categorical variables.
Data presented as median (interquartile range)
P-values of <.05 are in bold.