Table 3. Baseline characteristics according to AR expression (N=37).
Low AR expressionN=20 (%) | High AR expressionN=17 (%) | p-value | |
---|---|---|---|
Age (median) | .942 | ||
Range | |||
<40 years old | 8 (40.0) | 7 (41.2) | |
≥40 years old | 12 (60.0) | 10 (58.8) | |
Histology | .504 | ||
Invasive ductal carcinoma | 19 (95.0) | 15 (88.2) | |
Other | 1 (5.0) | 2 (11.8) | |
Subtype | .001 | ||
ER+HER2- | 4 (20.0) | 8 (47.1) | |
ER+HER2+ | 1 (5.0) | 4 (23.5) | |
ER-HER2- | 13 (65.0) | 0 (0.0) | |
ER-HER2+ | 2 (10.0) | 5 (29.4) | |
Intrinsic subtype | .001 | ||
Luminal A | 3(15.0) | 4 (23.5) | |
Luminal B | 0 (0.0) | 6 (35.3) | |
Basal-like | 13 (65.0) | 1 (2.7) | |
Normal-like | 1 (5.0) | 1 (2.7) | |
HER2-enriched | 2 (10.0) | 6 (35.3) | |
BRCA1/2 | .349 | ||
Wild type | 2 (10.0) | 0 (0.0) | |
Mutated | 2 (10.0) | 1 (5.9) | |
Not tested | 16 (80.0) | 16 (94.1) | |
Cancer status | .080 | ||
Recurrent | 16 (80.0) | 9 (52.9) | |
Initially metastatic | 4 (20.0) | 8 (47.1) | |
Visceral metastasis | .942 | ||
Yes | 8 (40.0) | 7 (41.2) | |
Liver metastasis | 4 (50.0) | 4 (57.1) | |
Brain metastasis | 4 (50.0) | 3 (42.9) | |
No | 12 (60.0) | 10 (58.8) | |
PIK3CA (N=34) | .013 | ||
Mutated | 2 (11.1) | 8 (50.0) | |
Wild type | 16 (88.9) | 8 (50.0) | |
TP53 (N=34) | .071 | ||
Mutated | 10 (55.6) | 4 (25.0) | |
Wild type | 8 (44.4) | 12 (75.0) |