Table 2. Subgroup analysis according to miRNA expression with prognosis.
| No. of studies | miRNA | HR | 95% CI of HR | Heterogeneity I2 (%) | Model used | |
|---|---|---|---|---|---|---|
| Worse prognosis with high miRNA expression | ||||||
| OS | 8 | 210, 17-92, 128, 9, 214, 130b, 130a, 199b-5p | 0.46 | 0.35-0.60 | 0 | Fixed effect |
| EFS | 8 | 210, 17-92, 128, 214, 542-5p, 130b, 130a, 199b-5p | 0.46 | 0.35-0.60 | 0 | Fixed effect |
| Worse prognosis with low miRNA expression | ||||||
| OS | 16 | 132, 145, 382, 133a, 26a, 340, 20a, 92a, 143, 451, 144, 22, 195, 124, 449a, 99a, 224 | 2.25 | 1.90-2.66 | 0 | Fixed effect |
| EFS | 8 | 132, 145, 382, 26a, 340, 451, 22, 99a | 2.05 | 1.67-5.18 | 0 | Fixed effect |
- HR, hazard ratio; OS, overall survival; EFS, event free survival