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. 2017 Jan 2;8(5):8791–8800. doi: 10.18632/oncotarget.14456

Figure 4. CS induced alterations of EMT markers in the bladder of mice exposed to CS for 12 weeks.

Figure 4

A. CS decreased the protein levels of E-cadherin and ZO-1, and increased the protein levels of Vimentin and N-cadherin in the bladder of mice. B. CS reduced mRNA levels of E-cadherin and ZO-1, and increased the protein levels of Vimentin and N-cadherin in the bladder of mice. C. CS increased ERK1/2, p38 and JNK activation in the bladder of mice. Data are expressed as mean ±SD. * p< 0.05 and ** p < 0.01, compared with FA control. FA = filtered air; CS = cigarette smoke.