Skip to main content
. Author manuscript; available in PMC: 2018 Apr 1.
Published in final edited form as: Respirology. 2016 Oct 19;22(3):486–493. doi: 10.1111/resp.12920

Figure 1. Increased plasma MMP-7 concentrations differentiate patients with IPF from controls.

Figure 1

A) Whisker Box-plots showing that plasma MMP-7 concentrations were significantly higher in patients with IPF compared to control subjects (12.07 vs 5.12 ng/ml, 95% CI: 11.32 – 14.58 vs. 4.63 – 6.45, *p<0.001), B) Diagnostic accuracy of plasma MMP-7 for IPF is presented by receiver operating characteristic (ROC) curve analysis. ROC curve analysis identified the optimal cut-off concentrations of plasma MMP-7 (8.18 ng/ml) that could differentiate patients with IPF from controls with the highest sensitivity (87.63) and specificity (82.93). The area under the curve (AUC) between patients with IPF and control subjects was 0.92.