Table 3. Sensitivity analysis of efficacy.
Sensitivity analysis | Symptom score | Medication score | ||||
---|---|---|---|---|---|---|
No. of studies | SMD (95% CI) | P value | No. of studies | SMD (95% CI) | P value | |
Fixed−effects model | 25 | −0.69 [−0.78, −0.60] | <0.00001 | 15 | −0.57 [−0.67, −0.47] | <0.00001 |
Excluded small studies (n<30) | 15 | −1.62 [−2.28, −0.96] | <0.00001 | 9 | −1.31 [−1.89, −0.74] | <0.00001 |
Excluded open label trials | 22 | −1.19 [−1.74, −0.65] | <0.0001 | 12 | −1.00 [−1.42, −0.58] | <0.00001 |
Excluded high drop out rate (≤20%) | 20 | −1.16 [−1.73, −0.59] | <0.0001 | 13 | −1.53 [−2.09, −0.97] | <0.00001 |
CI, confidence interval; SMD, standardized mean difference.