Table 2.
Female reproductive and post-reproductive circulating sex hormone concentrations
| 17β-estradiol | FSH | LH | |||||||
|---|---|---|---|---|---|---|---|---|---|
| ng/mL | Ratio | ng/mL | Ratio | ng/mL | Ratio | ||||
| Reproductivea | Post-reproductiveb | Fold change | Reproductivea | Post-reproductiveb | Fold change | Reproductivea | Post-reproductiveb | Fold change | |
| Human (Homo sapiens) | 0.15 (Mayo Clinic; Quest Diagnostics) |
0.02 (Mayo Clinic; Quest Diagnostics) |
−7.5 | 10 (Mayo Clinic; Quest Diagnostics) |
50 (Mayo Clinic; Quest Diagnostics) |
5.0 | 5 (Mayo Clinic; Quest Diagnostics) |
20 (Mayo Clinic; Quest Diagnostics) |
4.0 |
| Chimpanzee (Pan troglodytes) | 0.048 (Videan et al. 2008) |
0.030 (Videan et al. 2008) |
−1.6 | 4 (Videan et al. 2008) |
17 (Videan et al. 2008) |
4.2 | 1.0 (Videan et al. 2008) |
0.3 (Videan et al. 2008) |
3.3 |
| Rhesus Monkey (Macaca mulatta) | 0.070 (Downs and Urbanski 2006; Gore et al. 2004) |
0.038 (Downs and Urbanski 2006; Gore et al. 2004) |
−1.8 | 1.4 (Downs and Urbanski 2006; Gore et al. 2004) |
5.0 (Downs and Urbanski 2006; Gore et al. 2004) |
3.6 | 24 (Downs and Urbanski 2006; Gore et al. 2004) |
59 (Downs and Urbanski 2006; Gore et al. 2004) |
2.5 |
| Rat (Rattus norvegicus) | 0.033 (Goya et al. 1990) |
0.032 (Goya et al. 1990) |
−1.0 | 1.9 (Kurosumi et al. 1991) |
3.2 (Kurosumi et al. 1991) |
1.7 | 0.29 (Kurosumi et al. 1991) |
0.60 (Kurosumi et al. 1991) |
2.1 |
| Mouse (Mus musculus) | 0.097 (Cousins et al. 2003) |
0.036 (Cousins et al. 2003) |
−2.7 | 5 (Belisle et al. 1990) |
39 (Belisle et al. 1990) |
7.8 | 2 (Belisle et al. 1990) |
13 (Belisle et al. 1990) |
6.5 |
| Salmon (Oncorhynchus nerka) | 18.5 (Truscott et al. 1986) |
1.2 (Truscott et al. 1986) |
−15.4 | 2 (Truscott et al. 1986)c |
90 (Truscott et al. 1986)c |
45 | – | – | – |
aRepresentative mean hormone concentration across the estrus/menstrual cycle
bRepresentative mean hormone concentrations for post-reproductive animals
cValues for salmon represent total gonadotropins using antiserum raised against chum salmon gonadotropin preparation G7511 (Idler et al. 1975; Truscott et al. 1986). Summing the gonadotropin (LH and FSH) concentrations for iteroparous species (to allow comparison with the salmon gonadotropin concentrations) does not greatly alter the fold changes in concentrations between the reproductive and post-reproductive periods.
Where possible hormone concentrations from the same rodent strains have been compared