TABLE 3.

MICs for M. tuberculosis isolates from the 10 patients with variant fingerprint types among their clones

Patientb	Strain identity	DST result or MIC (μg/ml)a
		INH	RIF	STR
1	Primary isolate	Sensitive	Sensitive	Sensitive
	Strain 1	<0.05	<10	<1
	Strain 2	<0.2	<10	<1
2	Primary isolate	Sensitive	Sensitive	Sensitive
	Predominant spoligotype	<0.2	<10	<1
	Variant spoligotype	<0.05	<10	<1
3	Primary isolate	Sensitive	Sensitive	Sensitive
	Predominant spoligotype	<0.2	<10	<2
	Variant spoligotype	<0.05	<10	<4
4	Primary isolate	Sensitive	Sensitive	Sensitive
	Predominant spoligotype	<0.05	<10	<1
	Variant spoligotype	<3.2	<10	<1
5	Primary isolate	Sensitive	Sensitive	Sensitive
	Predominant spoligotype	<0.2	<20	<1
	Variant spoligotype	<0.05	<10	<1
6	Primary isolate	Sensitive	Sensitive	Sensitive
	Predominant spoligotype	<0.05	<10	<1
	Variant spoligotype	<0.05	<10	<1
7	Primary isolate	Sensitive	Sensitive	Sensitive
	Predominant spoligotype	<0.05	<10	<1
	Variant spoligotype	<0.2	<10	<1
8	Primary isolate	Resistant	Sensitive	Resistant
	Strain 1	<0.2	<10	>16
	Strain 2	<0.05	<10	<1
	Strain 3	<0.8	<20	>16
	Strain 4	<0.2	<10	<1
9	Primary isolate	Resistant	Resistant	Resistant
	Predominant RFLP type	>3.2	>80	>16
	Variant RFLP type	>3.2	>80	>16
10	Primary isolate	Sensitive	Sensitive	Sensitive
	Predominant RFLP type	<0.2	<10	<1
	Variant RFLP type	<0.2	<10	<1

^aOnly normal DST results (on L-J slants) obtained with critical concentrations, 0.2 μg/ml (and 1.0 μg/ml) for isoniazid, 40 μg/ml for rifampin, and 4 μg/ml for streptomycin, are reported for the primary isolates. MICs were determined on L-J slants. INH, isoniazid, RIF, rifampin, STR, streptomycin.

^bPatient designations are the same as those in Table 2.