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. 2017 Mar 16;8:293. doi: 10.3389/fimmu.2017.00293

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Copyright © 2017 Stabile, Fionda, Gismondi and Santoni.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Shaping natural killer (NK) cell subsets in tumor microenvironment. The main cellular and soluble factors affecting NK cell subset distribution in tumor microenvironment are shown. Melanoma and AML are reported as examples of solid and hematological tumor, respectively. For melanoma, tumor and metastatic lymph node (M-LN) infiltrating NK cell subsets are represented. For AML, bone marrow and peripheral blood NK cell subpopulations are indicated.