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. 2016 Dec 13;101(7):2831–2842. doi: 10.1007/s00253-016-8038-y

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© The Author(s) 2016

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 1 — Reaction catalyzed by F₄₂₀-dependent dehydrogenase (FGD). Glucose-6-phosphate is oxidized into 6-phosphogluconolactone by FGD concomitantly with the formation of the reduced F₄₂₀ coenzyme, which is subsequently employed by various F₄₂₀H₂-dependent reductases