Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Feb 7;12(Suppl 1):2–11. doi: 10.1007/s11789-017-0085-0

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2017

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

PMC Copyright notice

Fig. 1 — Extra- and intracellular PCSK9 has multiple targets including receptors and transporters, but it also modifies apolipoprotein B48 and apolipoprotein (a) expression (for details, see text). LRP1 Low density lipoprotein receptor (LDLR) related protein 1, VLDLR very low density lipoprotein receptor, ApoER apolipoprotein E receptor, CD36 cluster of differentiation 36, NPC1L1 Niemann-Pick C1-like protein 1, apo B48 apolipoprotein B48, apo (a) apolipoprotein (a), – indicates down-regulation or inhibitio, + indicates up-regulation