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Estimated sample size (with 20% loss) based on standard deviation (SD) within groups and correlation among baseline and 3 repeated measures [80% power, P=.05, 15% difference].
| SD within group/ correlation repeated measure |
Low repeated correlation (SD 0.2) | Mid repeated correlation (SD 0.5) | High repeated correlation (SD 0.8) |
| Low subject variation (SD 0.2) | 31 | 46 | 60 |
| Mid subject variation (SD 0.5) | 170 | 262 | 360 |
| High subject variation (SD 0.8) | 432 | 674 | 914 |
