Table 3.
Correlation of the clinicopathological parameters with Dicer, Drosha, AGO2, and DGCR8 mRNA expression levels in white American patients of the TCGA.
| Dicer | P | Drosha | P | DGCR8 | P | AGO2 | P | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Low | High | Low | High | Low | High | Low | High | |||||
| Age | 0.921a | 0.641a | 0.877a | 0.507a | ||||||||
| <40 | 9 | 7 | 10 | 6 | 8 | 8 | 11 | 5 | ||||
| 41–50 | 5 | 3 | 3 | 5 | 3 | 5 | 4 | 4 | ||||
| >50 | 4 | 3 | 4 | 3 | 4 | 3 | 4 | 3 | ||||
| Histologic Stage |
0.901a | 0.743a | 0.595a | 0.434a | ||||||||
| (i) | 13 | 8 | 12 | 9 | 10 | 11 | 14 | 7 | ||||
| (ii) | 2 | 3 | 2 | 3 | 2 | 3 | 2 | 3 | ||||
| (iii) | 2 | 2 | 3 | 1 | 2 | 2 | 3 | 1 | ||||
| (iv) | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | ||||
| T stage | 0.689a | 0.444a | 0.489a | 0.187a | ||||||||
| (1) | 5 | 2 | 4 | 3 | 3 | 4 | 3 | 4 | ||||
| (2) | 7 | 6 | 8 | 5 | 6 | 7 | 7 | 6 | ||||
| (3) | 5 | 5 | 5 | 5 | 5 | 5 | 9 | 1 | ||||
| (4) | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | ||||
| N stage | 1.000b | 0.269b | 0.143b | 0.264c | ||||||||
| (+) | 9 | 6 | 7 | 8 | 9 | 6 | 11 | 4 | ||||
| (−) | 9 | 6 | 10 | 5 | 5 | 10 | 7 | 8 | ||||
| M stage | 1.000c | 0.433c | 1.000c | 0.414c | ||||||||
| (+) | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | ||||
| (−) | 16 | 12 | 17 | 12 | 14 | 14 | 17 | 11 | ||||
| Multifocality | 0.621c | 0.607c | 1.000c | 0.605c | ||||||||
| (+) | 3 | 1 | 3 | 1 | 2 | 2 | 3 | 1 | ||||
| (−) | 15 | 12 | 14 | 13 | 13 | 14 | 16 | 16 | ||||
aLinear by linear association.
bChi-squared test.
cFisher's Exact test.