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. 2017 Mar 14;23(10):1764–1770. doi: 10.3748/wjg.v23.i10.1764

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©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.

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Size distribution of hepatocyte nuclei, the only evident change being detected after 24 h. A: Showing nuclear size distribution over time following PH. The most prominent change is observed at 24 h post-PH (green line), with the appearance of a larger nuclear class size (arrow), which is only marginally present at later time points; B: Reporting percent of binucleated hepatocytes detected on 2D sections in control rat liver and at 10 d post-PH. A relative decrease is observed after PH; C (control rat liver) and D (10 d post-PH) show immunofluorescent staining for Phalloidin with nuclei were counterstained with DAPI. Binucleated hepatocytes are easily discerned. Data are mean ± SE of 5 animals per group. ^bP < 0.01, vs control group. PH: Partial surgical hepatectomy.