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Number of Foxp3+ cells in the lymphocytic foci of BD-MSC treated and nontreated NOD mice. Following 4 weeks of treatment lacrimal glands were removed and processed for paraffin embedding. The glands were sectioned and stained for Foxp3 to identify regulatory T cells in the lymphocytic foci of (a) PBS treated and (b) BD-MSC treated mice. (c) The number of regulatory T cells per lymphocytic focus was then counted. Data are presented as means ± SEM (n = 3 for each group).
