Table 1.
Patient | Age (years) Sex | Development of NCs | Type of NC(s) | Symptoms | Indication for RT | Cause(s) of NC(s) | Diagnostic tools used | ||
---|---|---|---|---|---|---|---|---|---|
EMG | EEG | MRI | |||||||
1 | 40/M | Before RT | Tremor | Hand tremor | Glomerulonephritis | Tacrolimus | − | − | − |
2 | 32/F | Before RT | Tremor | Hand tremor | Polycystosis | Tacrolimus | − | − | − |
3 | 33/M | 15 days | Tremor | Hand and Leg tremor | Chronic renal failure | Tacrolimus | − | − | − |
4 | 56/M | 15 days | Tremor | Hand and Leg tremor | Polycystosis | Tacrolimus | − | − | − |
15 days | Polyneuropathy | Leg weakness and sensory disturbances | Polycystosis | Tacrolimus | + | − | − | ||
5 | 37/F | 15 days | Tremor | Hand and Leg tremor | UTI | Tacrolimus | − | − | − |
6 | 35/M | Before RT | Tremor | Hand tremor | Unknown | Cyclosporine | − | − | − |
7 | 23/F | 1 week | Tremor | Hand tremor | Hypertension | Tacrolimus | − | − | − |
4 months | Depression | Depression | Hypertension | Tacrolimus | − | − | − | ||
8 | 32/F | 1.5 months | Encephalopathy | Confusion | Unknown | Tacrolimus | − | + | + |
2 months | Polyneuropathy | Weakness in limbs | Unknown | Cyclosporine | + | − | − | ||
9 | 65/M | 7 months | Dementia Delirium | Delirium | Hypertension | Infection | − | + | − |
10 | 55/M | 4 years | Lumbar radiculopathy | Unilateral thigh pain | Diabetes mellitus and hypertension | Unknown | + | − | − |
11 | 18/M | 5 years | Polyneuropathy | Unilateral thigh pain and leg weakness | Amyloidosis and FMF | Amyloidosis | + | − | − |
12 | 36/M | 4 years | Polyneuropathy | Sensory ataxia | Unknown | Cyclosporine | + | − | − |
13 | 48/M | 4 months | Sensory disturbance | Hand numbness | Bilateral nephrolithotomy | Tacrolimus | + | − | − |
14 | 26/M | 2 years | Seizure | GTC seizure | Policystosis | Tacrolimus | − | + | + |
15 | 42/F | 5 years | Status epilepticus | GTC seizures | Diabetes mellitus | Hypoglycemia | − | + | − |
16 | 36/M | 4 years | Status epilepticus | GTC seizures | Nephritis | Tacrolimus | − | + | − |
17 | 23/F | 6 years | Headache | Headache | Unknown | Tacrolimus | − | − | − |
18 | 22/F | 10 days | Seizure | GTC seizure | Bilateral renal atrophy | Septic emboli | − | + | − |
19 | 54/F | 4 days | Encephalopathy | Confusion GTC seizures | Unknown | Tacrolimus | − | + | + |
RT: renal transplantation; EEG: electroencephalography; EMG: electroneuromyography; MRI: brain magnetic resonance imaging; NCs: neurological complications; UTI: urinary tract infection; PNP: polyneuropathy; FMF: familial Mediterranean fever